Author: Amit S. Kalgutkar
Edition: 1
Binding: Hardcover
ISBN: 3527330852
Edition: 1
Binding: Hardcover
ISBN: 3527330852
Reactive Drug Metabolites (Methods and Principles in Medicinal Chemistry)
Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the largest
pharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite toxicity, covering basic concepts and techniques in the process, while the second part details chemical toxicophores that are prone to reactive metabolite formation. This section also reviews the various drug-metabolizing enzymes that can participate in catalyzing reactive metabolite formation, including a discussion of the structure-toxicity relationships for drugs. Two chapters are dedicated to the currently hot topics of herbal constituents and IADRs.
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Reactive Drug Metabolites By Amit S Kalgutkar. H Isbn13: 9783527330850
author amit s kalgutkar author deepak dalvie author douglas a smith author r scott obach format hardback language english publication year 24 10 2012 series methods principles in medicinal chemistry subject medicine subject 2 clinical medicine professional reactive drug metabolites by amit s kalgutkar h isbn 13 9783527330850 author biography amit kalgutkar received his academic degrees from the university of bombay india and from virginia polytechnic institute usa joining pfizer in 1999 he is cu
Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the largest
pharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite toxicity, covering basic concepts and techniques in the process, while the second part details chemical toxicophores that are prone to reactive metabolite formation. This section also reviews the various drug-metabolizing enzymes that can participate in catalyzing reactive metabolite formation, including a discussion of the struc
pharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite toxicity, covering basic concepts and techniques in the process, while the second part details chemical toxicophores that are prone to reactive metabolite formation. This section also reviews the various drug-metabolizing enzymes that can participate in catalyzing reactive metabolite formation, including a discussion of the struc
Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the largest pharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite toxicity, covering basic concepts and techniques in the process, while the second part details chemical toxicophores that are prone to reactive metabolite formation. This section also reviews the various drug-metabolizing enzymes that can participate in catalyzing reactive metabolite formation, including a discussion of the struc
Categories: Medicine - Pharmacology * General. Contributors: Amit S. Kalgutkar - Author. Format: Hardcover
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